Treating symptoms of declined mental capacity (memory, mood, and behavior problems) in certain patients older than 60 years of age. It may also be used for other conditions as determined by your doctor.

Hydergine is an ergot alkaloid. Exactly how it works is unknown.

There is no specific evidence which clearly establishes the mechanism by which Hydergine® (ergoloid mesylates) preparations produce mental effects, nor is there conclusive evidence that the drug particularly affects cerebral arteriosclerosis or cerebrovascular insufficiency.
Hydergine® (ergoloid mesylates) preparations are contraindicated in individuals who have previously shown hypersensitivity to the drug. Hydergine® (ergoloid mesylates) preparations are also contraindicated in patients who have psychosis, acute or chronic, regardless of etiology.