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Dovonex

COMPOSITION:
Each gram of cream contains:
Calcipotriol hydrate equivalent to
Calcipotriol (anhydrous)
        50 micrograms
Preservatives: 
Chloroallylhexaminium chloride 0,05% m/m
Disodium edetate 0,05%m/m
Each gram of ointment contains:        
Calcipotriol (anhydrous)         50 micrograms.
Each mL of scalp solution contains:        
Calcipotriol hydrate equivalent to
Calcipotriol (anhydrous)
        50 micrograms.

PHARMACOLOGICAL CLASSIFICATION:
A 13. 9.1 Preparations for psoriasis

PHARMACOLOGICAL ACTION:
Calcipotriol is a Vitamin D analogue. Topical application will induce differentiation and suppress proliferation of keratinocytes, thus reversing the abnormal keratinocyte changes in psoriasis.
Studies in psoriatic patients demonstrate less than 1% absorption of the applied dose.

INDICATIONS:
DOVONEX Cream
and Ointment are indicated for the topical treatment of psoriasis vulgaris, mainly plaque psoriasis. DOVONEX Scalp Solution is indicated for the topical treatment of scalp psoriasis.

CONTRA-INDICATIONS:
Hypersensitivity to any of the constituents.
Hypercalcaemia.
Safety in pregnancy and lactation has not been established.
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